Short-Term Effects

• Lowered inhibitions/poor social judgement
• Skin flushing
• Trouble concentrating
• Loss of coordination
• Slower brain activity
• Sleepiness 
• Mood swings
• Dulled perceptions, especially in vision and hearing
• Dilated pupils
• Reduced core body temperature
• Raised blood pressure and heart rate
• Stumbling
• Passing out
• Vomiting
• Shallow, irregular, or slow breathing
• Blackouts

Long-Term Effects

• Damage to different regions of the brain 
• Addiction
• Heart disease
• Liver disease
• Respiratory infections
• Cancer
• Nerve damage
• Ulcers
• Sexual problems
• Malnutrition